Meet Spot, a clever little dog with big dreams of becoming a real boy. When Spot finds out that a crazy scientist can make his wish come true, he takes a cross-country trek with Leonard, his best friend and master, and their mom. However, Dr. Krank's experiments are a little less than perfect, and it will take Leonard and his pet pals to right this genetic wrong.

Cast: Nathan Lane, Kelsey Grammer, Shaun Fleming, Debra Jo Rupp, David Ogden Stiers, Jerry Stiller